What is the FMS action level for Endotoxin for water in the tank, piping, and distribution loop?

The FMS action level for endotoxin in water systems, particularly in contexts such as tank storage, piping, and distribution loops, is set at 0.125 EU/ml. This threshold is established to ensure that the quality of the water used in medical settings, especially those related to dialysis and other treatments, is safe and effective for patient care.

Endotoxins are components of the cell wall of gram-negative bacteria, and their presence in water systems can pose severe risks to patients, especially those who are immunocompromised or undergoing treatments that require high-purity water. Monitoring endotoxin levels at this specified action level allows for appropriate measures to be taken if the levels exceed that threshold, thereby maintaining safety and compliance with health standards.

In addition, the specific value of 0.125 EU/ml reflects the guidelines set forth by clinical and regulatory standards aimed at minimizing the risk of endotoxin-related adverse effects, highlighting its significance in ensuring the overall integrity of water treatment processes.